hrp0082p2-d1-517 | Pituitary | ESPE2014

Could Brain MRI Replace GH Stimulation Tests in the Work-Up of GH Deficiency in the First Years of Life?

Pedicelli Stefania , Scire Giuseppe , Pampanini Valentina , Gubinelli Jessica , Spadoni Gian Luigi , Bitti Maria Luisa Manca , Cappa Marco , Boscherini Brunetto , Cianfarani Stefano

Background: Currently, the diagnosis of GH deficiency (GHD) in infants and young children is based on the assessment of GH serum levels either during hypoglycaemia or after pharmacological stimulation tests. However, GH cut-off values have not been standardized and provocative tests may be unsafe in this age range.Objective and hypotheses: Brain MRI may replace GH measurements in diagnosing GHD in infancy and young childhood.Method...